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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC9A1
All Species:
9.7
Human Site:
S616
Identified Species:
17.78
UniProt:
P19634
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19634
NP_003038.2
815
90763
S616
I
H
P
K
S
L
P
S
E
R
I
L
P
A
L
Chimpanzee
Pan troglodytes
XP_513239
793
88468
E615
P
A
L
S
K
D
K
E
E
E
I
R
K
I
L
Rhesus Macaque
Macaca mulatta
XP_001115213
427
46791
V259
N
E
L
L
H
I
L
V
F
G
E
S
L
L
N
Dog
Lupus familis
XP_535345
816
90951
A617
I
H
P
K
S
L
P
A
E
R
I
L
P
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61165
820
91449
S620
I
H
P
K
A
V
T
S
D
R
I
L
P
A
L
Rat
Rattus norvegicus
P26431
820
91629
S620
I
H
P
K
S
A
A
S
E
R
I
L
P
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514675
940
104115
P723
E
K
I
R
K
L
T
P
V
E
M
D
E
M
R
Chicken
Gallus gallus
Q5ZJ75
574
64115
T406
F
F
R
D
H
K
I
T
P
K
M
M
F
I
M
Frog
Xenopus laevis
NP_001081553
781
87800
A596
I
Q
P
K
P
K
L
A
E
R
F
I
P
T
L
Zebra Danio
Brachydanio rerio
NP_001106952
653
73606
H485
C
G
H
Y
G
H
H
H
W
R
D
K
I
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35449
667
75263
P499
F
N
A
K
V
I
K
P
V
L
M
R
H
Q
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWU6
535
59320
N367
F
G
C
G
Y
L
V
N
L
A
R
P
A
H
R
Baker's Yeast
Sacchar. cerevisiae
Q04121
633
70130
L465
F
T
L
L
A
T
V
L
V
V
V
V
L
T
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.3
51.9
95.8
N.A.
92.4
93.2
N.A.
42.5
21.7
73.2
55.4
N.A.
N.A.
N.A.
33.1
N.A.
Protein Similarity:
100
86.9
52
97.5
N.A.
95
95.1
N.A.
57.7
39.7
81.8
68.9
N.A.
N.A.
N.A.
52.5
N.A.
P-Site Identity:
100
20
0
93.3
N.A.
73.3
86.6
N.A.
6.6
0
46.6
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
20
6.6
100
N.A.
93.3
86.6
N.A.
20
33.3
60
13.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.5
41.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
16
8
8
16
0
8
0
0
8
31
0
% A
% Cys:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
0
0
8
0
8
8
0
0
0
% D
% Glu:
8
8
0
0
0
0
0
8
39
16
8
0
8
0
0
% E
% Phe:
31
8
0
0
0
0
0
0
8
0
8
0
8
0
0
% F
% Gly:
0
16
0
8
8
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
31
8
0
16
8
8
8
0
0
0
0
8
8
0
% H
% Ile:
39
0
8
0
0
16
8
0
0
0
39
8
8
16
0
% I
% Lys:
0
8
0
47
16
16
16
0
0
8
0
8
8
0
8
% K
% Leu:
0
0
24
16
0
31
16
8
8
8
0
31
16
8
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
24
8
0
8
8
% M
% Asn:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
8
0
39
0
8
0
16
16
8
0
0
8
39
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
8
8
0
0
0
0
0
47
8
16
0
0
24
% R
% Ser:
0
0
0
8
24
0
0
24
0
0
0
8
0
8
0
% S
% Thr:
0
8
0
0
0
8
16
8
0
0
0
0
0
16
0
% T
% Val:
0
0
0
0
8
8
16
8
24
8
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _